Welcome Empagliflozin ! ASCVD, Heart Failure and CVD death
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منابع مشابه
Empagliflozin and the Prevention of Heart€Failure
SEE PAGE 347 H eart failure develops in more than 1 in 5 patients with diabetes mellitus (DM) older than 65 years of age and augers an extremely poor prognosis, with a median survival of approximately 4 years. The landmark EMPA-REG OUTCOME (Empagliflozin Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients) showed that empagliflozin significantly reduced the primary composite...
متن کاملPulmonary Pressures and Death in Heart Failure
Accreditation and Designation Statement The American College of Cardiology Foundation (ACCF) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. The ACCF designates this Journal-based CME activity for a maximum of 1 AMA PRA Category 1 Credit(s). Physicians should only claim credit commensurate with the exten...
متن کاملDeath begets failure in the heart.
Recently, low--but abnormal--rates of cardiomyocyte apoptosis have been observed in failing human hearts. Genetic and pharmacological studies suggest that this cell death is causally linked to heart failure in rodent models. Herein, we review these data and discuss potential therapeutic implications.
متن کاملChronobiology of death in heart failure.
INTRODUCTION AND OBJECTIVES In the general population, heart events occur more often during early morning, on Mondays, and during winter. However, the chronobiology of death in heart failure has not been analyzed. The aim of this study was to determine the circadian, day of the week, and seasonal variability of all-cause mortality in chronic heart failure. METHODS This was an analysis of all ...
متن کاملWhat causes sudden death in heart failure?
Patients with heart failure experience a number of changes in the electrical function of the heart that predispose to potentially lethal cardiac arrhythmias. Action potential prolongation, the result of functional downregulation of K currents, and aberrant Ca2+ handling is a recurrent theme. Significant alterations in conduction and activation of a number of initially adaptive but ultimately ma...
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ژورنال
عنوان ژورنال: Cardiovascular Journal
سال: 2019
ISSN: 2309-6357,2071-0917
DOI: 10.3329/cardio.v12i1.43410